Search by BoMiProt ID - Bomi5713


Primary Information

BoMiProt ID Bomi5713
Protein Name Fatty acid desaturase 6
Organism Bos taurus
Uniprot IdA2VE15
Milk FractionWhey,exosome
Ref Sequence Id NP_001075191.1
Aminoacid Length 342
Molecular Weight 38614
Fasta Sequence https://www.uniprot.org/uniprot/A2VE15.fasta
Gene Name FADS6
Gene Id 523867
Protein Existence Status reviewed

Secondary Information

Protein Function Fatty acid desaturase 6 is one of the Fattyacid desaturase which plays key roles in synthesizing Polyunsaturated fatty acids (PUFAs).
Biochemical Properties It is involved in the pathway of fatty acid metabolism, which is a part of Lipid metabolism.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (1-13)
DisProt Annotation
TM Helix Prediction 2TMHs; (65-83),(152-170)
Additional Comments Peroxisome proliferator-activated receptor alpha b (PPARαb) played a vital role in ToFads6 regulation and may promote the biosynthesis of long-chain polyunsaturated fatty acids by regulating ToFads6 expression.
Bibliography 1.Zhu KC, Song L, Guo HY, Guo L, Zhang N, Liu BS, Jiang SG, Zhang DC. Identification of Fatty Acid Desaturase 6 in Golden Pompano Trachinotus Ovatus (Linnaeus 1758) and Its Regulation by the PPARαb Transcription Factor. Int J Mol Sci. 2018 Dec 21;20(1):23. doi: 10.3390/ijms20010023. PMID: 30577588; PMCID: PMC6337163. 2.Lee JM, Lee H, Kang S, Park WJ. Fatty Acid Desaturases, Polyunsaturated Fatty Acid Regulation, and Biotechnological Advances. Nutrients. 2016 Jan 4;8(1):23. doi: 10.3390/nu8010023. PMID: 26742061; PMCID: PMC4728637.