Search by BoMiProt ID - Bomi5623


Primary Information

BoMiProt ID Bomi5623
Protein Name Eukaryotic translation initiation factor 3 subunit L/Eukaryotic translation initiation factor 3 subunit 6-interacting protein/Eukaryotic translation initiation factor 3 subunit E-interacting protein
Organism Bos taurus
Uniprot IdQ3ZCK1
Milk FractionExosomes
Ref Sequence Id NP_001030373.1
Aminoacid Length 564
Molecular Weight 66727
Fasta Sequence https://www.uniprot.org/uniprot/Q3ZCK1.fasta
Gene Name EIF3L
Gene Id 514449
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells myometrium
Protein Function The 67-kDa L subunit of human eukaryotic translation initiation factor 3 (eIF3L) is one of the subunits of the mammalian translation initiation factor eIF3. The eIF3 factor plays a central role in translation initiation by recruiting the 40S ribosomal subunit and keeping it dissociated from the 60S subunit and by promoting the association of the former with mRNA and initiator Met-tRNA.
PTMs N6-acetylation at lysine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Morris-Desbois C, Réty S, Ferro M, Garin J, Jalinot P. The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3. J Biol Chem. 2001;276:45988–45995. doi: 10.1074/jbc.M104966200. 2.