Search by BoMiProt ID - Bomi5555


Primary Information

BoMiProt ID Bomi5555
Protein Name ER lumen protein-retaining receptor 2/KDELR2/KDEL receptor 2
Organism Bos taurus
Uniprot IdQ2KJ37
Milk Fractionwhey
Ref Sequence Id NP_001073247.1
Aminoacid Length 212
Molecular Weight 24454
Fasta Sequence https://www.uniprot.org/uniprot/Q2KJ37.fasta
Gene Name KDELR2
Gene Id 531676
Protein Existence Status Reviewed

Secondary Information

Protein Function It serves as receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum
Biochemical Properties Interaction with the K-D-E-L motif on target proteins
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
NA
Predicted Disorder Regions (203-212)
DisProt Annotation
TM Helix Prediction 4TMHs; (56-78), (116-138), (151-169), (178-200)
Bibliography Liao, Z., She, C., Ma, L., Sun, Z., Li, P., Zhang, X., Wang, P., & Li, W. (2019). KDELR2 Promotes Glioblastoma Tumorigenesis Targeted by HIF1a via mTOR Signaling Pathway. Cellular and molecular neurobiology, 39(8), 1207–1215. https://doi.org/10.1007/s10571-019-00715-2