Primary Information |
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| BoMiProt ID | Bomi5333 |
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| Protein Name | Dynein regulatory complex protein 10/IQ domain-containing protein D |
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| Organism | Bos taurus |
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| Uniprot Id | Q17QH9 |
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| Milk Fraction | Whey |
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| Ref Sequence Id | NP_001069074.1 |
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| Aminoacid Length | 444 |
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| Molecular Weight | 51623 |
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| Fasta Sequence | https://www.uniprot.org/uniprot/Q17QH9.fasta |
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| Gene Name | IQCD |
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| Gene Id | 513272 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | imp for ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.role in sperm fertilisation and the acrosome reaction. |
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| Biochemical Properties | C-terminal conserved IQ motif domain and two coiled-coil domains |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 29-40, 422-444 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Zhang P, Jiang W, Luo N, Zhu W, Fan L. IQ motif containing D (IQCD), a new acrosomal protein involved in the acrosome reaction and fertilisation. Reprod Fertil Dev. 2019 Apr;31(5):898-914. doi: 10.1071/RD18416. Erratum in: Reprod Fertil Dev. 2019 Apr;31(5):1033. PMID: 30712531. |
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