Search by BoMiProt ID - Bomi5216


Primary Information

BoMiProt ID Bomi5216
Protein Name DNA-directed RNA polymerase II subunit GRINL1A/DNA-directed RNA polymerase II subunit M/Glutamate receptor-like protein 1A
Organism Bos taurus
Uniprot IdQ17QE3
Milk FractionExosomes
Ref Sequence Id NP_001098947.1
Aminoacid Length 370
Molecular Weight 41312
Fasta Sequence https://www.uniprot.org/uniprot/Q17QE3.fasta
Gene Name POLR2M
Gene Id 100125877
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells gluteal muscle 
Protein Function Appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II).May play a role in Mediator complex-dependent regulation of transcription activation.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 1-20, 43-56, 86-290, 308-370
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Hu X, Malik S, Negroiu CC, Hubbard K, Velalar CN, Hampton B, Grosu D, Catalano J, Roeder RG, Gnatt A. A Mediator-responsive form of metazoan RNA polymerase II. Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9506-11. doi: 10.1073/pnas.0603702103. Epub 2006 Jun 12. PMID: 16769904; PMCID: PMC1480437. 2.