Primary Information
BoMiProt ID	Bomi5084
Protein Name	Deoxyribose-phosphate aldolase/2-deoxy-D-ribose 5-phosphate aldolase/Phosphodeoxyriboaldolase/Deoxyriboaldolase/DERA
Organism	Bos taurus
Uniprot ID	Q3T0V9
Milk Fraction	Whey
Ref Sequence ID	NP_001069496.1
Aminoacid Length	318
Molecular Weight	35246
FASTA Sequence	Download
Gene Name	DERA
Gene ID	534558
Protein Existence Status	reviewed
Secondary Information
Protein Function	It's function is to minimize or delay stress-induced damage by producing energy through deoxynucleoside degradation.
Biochemical Properties	It converts 2-deoxy-d-ribose-5-phosphate into glyceraldehyde-3-phosphate and acetaldehyde, belongs to the core metabolism of living organisms.
PTMs	Phosphorylation at Serine
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Additional Comments	In Bacillus cereus dRib 5-P aldolase is involved in the catabolism of exogenous deox3,ribonucleosides. This spore-forming bacterium can grow on nucleosides as a carbon source, since it possesses an efficient catabolic pathway by which the pentose moiety of exogenous nucleosides may be utilized as an energy source
Bibliography	1.Salleron L, Magistrelli G, Mary C, Fischer N, Bairoch A, Lane L. DERA is the human deoxyribose phosphate aldolase and is involved in stress response. Biochim Biophys Acta. 2014 Dec;1843(12):2913-25. doi: 10.1016/j.bbamcr.2014.09.007. Epub 2014 Sep 16. PMID: 25229427. 2.Sgarrella F, Del Corso A, Tozzi MG, Camici M. Deoxyribose 5-phosphate aldolase of Bacillus cereus: purification and properties. Biochim Biophys Acta. 1992 Jan 9;1118(2):130-3. doi: 10.1016/0167-4838(92)90139-5. PMID: 1730028. 3. Mura. U.. Sgarrelta, F. and Ipata, P.L. (1978) J. Biol. Chem. 253, 79O5-7OO9. 4.lpata. P.L. Sgarrella. F. and Tozzi, M.G. (1985) Curt, Top. Ceil, Regul. 26, 4t9-432.