Search by BoMiProt ID - Bomi4943


Primary Information

BoMiProt ID Bomi4943
Protein Name C-X-C motif chemokine 17/VEGF coregulated chemokine 1
Organism Bos taurus
Uniprot IdA4IFR0
Milk FractionWhey
Ref Sequence Id NP_001077268.1
Aminoacid Length 118
Molecular Weight 13597
Fasta Sequence https://www.uniprot.org/uniprot/A4IFR0.fasta
Gene Name CXCL17/VCC1
Gene Id 788717
Protein Existence Status reviewed

Secondary Information

Protein Function Acts as chemoattractant for cells such as monocytes, macrophages and dendritic cells (Chemokine). Plays a role in angiogenesis. May also have role in the tumorigenesis. May have a potential role in the innate defense against infections.
Biochemical Properties Activates the C-X-C chemokine receptor GPR35 to induce a quick and shortlived increase in the level of intracellular calcium ions.
Significance in milk plays an important role in the bovine mammary gland immunity
PTMs Disulphide bond
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 2 disordered segments; (22-42), (72-100)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Zimin, A. V., Delcher, A. L., Florea, L., Kelley, D. R., Schatz, M. C., Puiu, D., Hanrahan, F., Pertea, G., Van Tassell, C. P., Sonstegard, T. S., Marçais, G., Roberts, M., Subramanian, P., Yorke, J. A., & Salzberg, S. L. (2009). A whole-genome assembly of the domestic cow, Bos taurus. Genome biology, 10(4), R42. https://doi.org/10.1186/gb-2009-10-4-r42