Search by BoMiProt ID - Bomi4794


Primary Information

BoMiProt ID Bomi4794
Protein Name Coiled-coil domain-containing protein 152
Organism Bos taurus
Uniprot IdQ32LM7
Milk FractionWhey
Aminoacid Length 240
Molecular Weight 28459
Fasta Sequence https://www.uniprot.org/uniprot/Q32LM7.fasta
Gene Name CCDC152
Protein Existence Status reviewed

Secondary Information

Protein Function Role in cell cycle regulation, cellular proliferation and migration.A high level of CCDC152 protein can not only suppress the bidirectional promoter activity, but also inhibit cell proliferation and migration; conversely, a low level of CCDC152 protein can increase bidirectional promoter activity, as well as promote cellular proliferation and migration by mediating JAK2/STAT3/5 signaling pathway.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 1-13, 28-38, 57-130, 142-156, 174-203, 214-240
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Lin, S., Luo, W., Jiang, M., Luo, W., Abdalla, B. A., Nie, Q., Zhang, L., & Zhang, X. (2017). Chicken CCDC152 shares an NFYB-regulated bidirectional promoter with a growth hormone receptor antisense transcript and inhibits cells proliferation and migration. Oncotarget, 8(48), 84039–84053. https://doi.org/10.18632/oncotarget.21091