Search by BoMiProt ID - Bomi4751


Primary Information

BoMiProt ID Bomi4751
Protein Name Coagulation factor XIII A chain/Coagulation factor XIIIa/Protein-glutamine gamma-glutamyltransferase A chain/Transglutaminase A chain
Organism Bos taurus
Uniprot IdP12260
Milk FractionWhey
Aminoacid Length 198
Molecular Weight 22745
Fasta Sequence https://www.uniprot.org/uniprot/P12260.fasta
Gene Name F13A1/F13A
Protein Existence Status reviewed

Secondary Information

Protein Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Biochemical Properties Catalyses L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N6-5-L-glutamyl-[protein] + NH4+. Binds 1 Ca2+ ion per subunit.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 1 predicted disorder segment;(1-35)
DisProt Annotation
TM Helix Prediction No TM helices