Search by BoMiProt ID - Bomi4586


Primary Information

BoMiProt ID Bomi4586
Protein Name Cell death activator CIDE-B/Cell death-inducing DFFA-like effector B
Organism Bos taurus
Uniprot IdQ3T191
Milk FractionWhey
Ref Sequence Id NP_001029739.1
Aminoacid Length 219
Molecular Weight 24650
Fasta Sequence https://www.uniprot.org/uniprot/Q3T191.fasta
Gene Name CIDEB
Gene Id 528834
Protein Existence Status reviewed

Secondary Information

Protein Function role in apoptosis.CIDE-B mediates cytochromec release from mitochondria and caspase 3 activity
Biochemical Properties strong cell death-inducing activity in its C-terminal domain.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 1-4, 26-43, 118-126, 211-219
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Erdtmann L, Franck N, Lerat H, Le Seyec J, Gilot D, Cannie I, Gripon P, Hibner U, Guguen-Guillouzo C. The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis. J Biol Chem. 2003 May 16;278(20):18256-64. doi: 10.1074/jbc.M209732200. Epub 2003 Feb 20. PMID: 12595532.