Search by BoMiProt ID - Bomi4152


Primary Information

BoMiProt ID Bomi4152
Protein Name ATPase family AAA domain-containing protein 3
Organism Bos taurus
Uniprot IdA7YWC4
Milk FractionWhey
Ref Sequence Id NP_001098932.1
Aminoacid Length 586
Molecular Weight 66107
Fasta Sequence https://www.uniprot.org/uniprot/A7YWC4.fasta
Gene Name ATAD3
Gene Id 784353
Protein Existence Status reviewed

Secondary Information

Protein Function mitochondrial protein synthesis and participate in mitochondrial DNA replication..
Biochemical Properties a conserved C-terminal AAA+-ATPase domain (residues 320–518) that is present in flies, worms and mammals, characterized by ATP-binding and ATPase domains (Walker A and Walker B), including an SRH motif, sensor I and sensor II residues, and an arginine finger.
Significance in milk regulates milk biosynthesis and proliferation of mammary epithelial cells
PTMs Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 12-43, 137-149, 570-586
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Baudier J. ATAD3 proteins: brokers of a mitochondria-endoplasmic reticulum connection in mammalian cells. Biol Rev Camb Philos Soc. 2018 May;93(2):827-844. doi: 10.1111/brv.12373. Epub 2017 Sep 20. PMID: 28941010.