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Primary Information | |
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| BoMiProt ID | Bomi4130 |
| Protein Name | ATP synthase F(0) complex subunit B1, mitochondrial/ATP synthase peripheral stalk-membrane subunit b/ATP synthase subunit b |
| Organism | Bos taurus |
| Uniprot ID | P13619 |
| Milk Fraction | Whey |
| Ref Sequence ID | NP_001033590.1 |
| Aminoacid Length | 256 |
| Molecular Weight | 28822 |
| FASTA Sequence | Download |
| Gene Name | ATP5PB |
| Gene ID | 282701 |
| Protein Existence Status | Reviewed |
Secondary Information | |
| Presence in other biological fluids/tissue/cells | corpus luteum |
| Protein Function | Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. Part of the complex F0 domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha3beta3 subcomplex and subunit a/ATP6 static relative to the rotary elements. |
| Biochemical Properties | F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk |
| PTMs | N6-acetylation at Lysine |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | na |
| SCOP | Class : All alpha proteins Fold : ATP synthase B chain-like Superfamily : ATP synthase B chain-like Family : ATP synthase B chain-like Domain Name : 2CLY A:79-183 |
| CATH | Matched CATH superfamily 1.20.5.2210 |
| Predicted Disorder Regions | 42-47, 244-256 |
| DisProt Annotation | |
| TM Helix Prediction | No TM helices |
| PDB ID | 2CLY, 2WSS, 4B2Q, 5ARA, 5ARE, 5ARH, 5ARI, 5FIJ, 5FIK, 5FIL, 6YY0, 6Z1R, 6Z1U, 6ZBB, 6ZIQ, 6ZIT, 6ZIU, 6ZPO, 6ZQM, 6ZQN, 7AJB,7AJC, 7AJD, 7AJE, 7AJF, 7AJG, 7AJH, 7AJI, 7AJJ, |
| Bibliography | Walker JE, Runswick MJ, Poulter L. ATP synthase from bovine mitochondria. The characterization and sequence analysis of two membrane-associated sub-units and of the corresponding cDNAs. J Mol Biol. 1987 Sep 5;197(1):89-100. doi: 10.1016/0022-2836(87)90611-5. PMID: 2890767. |