Search by BoMiProt ID - Bomi3739


Primary Information

BoMiProt ID Bomi3739
Protein Name ADP-ribosylation factor-like protein 1
Organism Bos taurus
Uniprot IdQ2YDM1
Milk FractionWhey,Exosome,MFGM
Ref Sequence Id NP_001039694.1
Aminoacid Length 181
Molecular Weight 20428
Fasta Sequence https://www.uniprot.org/uniprot/Q2YDM1.fasta
Gene Name ARL1
Gene Id 517345
Protein Existence Status Reviewed

Secondary Information

Protein Function Arl1 is essential for formation of secretory granules in the larval salivary gland.It is a GTP-binding protein. It can activate phospholipase D (PLD) as well but with reduced efficiency. It is also important for normal function of the Golgi apparatus.Arl1 is required for secretory granule maturation.
Biochemical Properties The GTP-bound form interacts with GOLGA1, GOLGA4 and RGPD8. The GTP-bound form directly interacts with ARFIP2; this interaction leads to an increase in the amount of bound GTP at steady state level. Binds to SCOC, preferentially in its GTP-bound form. May interact with UNC119 
PTMs Myristoylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Lee, F. J., Huang, C. F., Yu, W. L., Buu, L. M., Lin, C. Y., Huang, M. C., Moss, J., & Vaughan, M. (1997). Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae. The Journal of biological chemistry, 272(49), 30998–31005. https://doi.org/10.1074/jbc.272.49.30998