Search by BoMiProt ID - Bomi3732


Primary Information

BoMiProt ID Bomi3732
Protein Name ADP/ATP translocase 3/Solute carrier family 25 member 6/Adenine nucleotide translocator 3
Organism Bos taurus
Uniprot IdP32007
Milk FractionWhey
Ref Sequence Id NP_777085.1
Aminoacid Length 298
Molecular Weight 32877
Fasta Sequence https://www.uniprot.org/uniprot/P32007.fasta
Gene Name SLC25A6
Gene Id 282480
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells  rumen papilla 
Protein Function Adenine nucleotide translocase (ANT) 3, an enzyme which exchanges ATP and ADP through mitochondrial membrane, has been identified as a novel target counter-regulated by IL-4 and IFN-gamma. 
PTMs N-acetylation at methionine,Trimethylation by ANTKMT at Lys-52
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 4-7, 40-53, 243-245
DisProt Annotation
TM Helix Prediction 2TMHs; (173-195),(210-231)
Additional Comments Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells
Bibliography 1.Jang JY, Lee CE. Mitochondrial adenine nucleotide translocator 3 is regulated by IL-4 and IFN-gamma via STAT-dependent pathways. Cell Immunol. 2003 Nov;226(1):11-9. doi: 10.1016/j.cellimm.2003.11.004. PMID: 14746803. 2.Zamora M, Granell M, Mampel T, Viñas O. Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells. FEBS Lett. 2004 Apr 9;563(1-3):155-60. doi: 10.1016/S0014-5793(04)00293-5. PMID: 15063741.