Search by BoMiProt ID - Bomi3702


Primary Information

BoMiProt ID Bomi3702
Protein Name Adenylyltransferase and sulfurtransferase MOCS3/Molybdenum cofactor synthesis protein 3/Sulfur carrier protein MOCS2A sulfurtransferase/Sulfurtransferase MOCS3/Molybdopterin-synthase sulfurtransferase/Sulfur carrier protein MOCS2A adenylyltransferase
Organism Bos taurus
Uniprot IdA1A4L8
Milk FractionWhey
Ref Sequence Id NP_001075203.1
Aminoacid Length 455
Molecular Weight 48834
Fasta Sequence https://www.uniprot.org/uniprot/A1A4L8.fasta
Gene Name MOCS3
Gene Id 539728
Protein Existence Status reviewed

Secondary Information

Protein Function take part in molybdopterin biosynthesis and Cofactor biosynthesis.
Biochemical Properties  Binds 1 zinc ion per subunit.MOCS3 structurally and functionally resembles the ubiquitin-activating enzyme E1.The C-terminus of MOCS3 has a rhodanese-like fold and transfer sulfur to be transferred to MOCS2A(subunit of MPT synthase) in the form of a persulfide group.
PTMs Disulfide formation
Linking IDs Bomi3702
Bibliography Neukranz Y, Kotter A, Beilschmidt L, Marelja Z, Helm M, Gräf R, Leimkühler S. Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. Biochemistry. 2019 Apr 2;58(13):1786-1798. doi: 10.1021/acs.biochem.8b01160. Epub 2019 Mar 13. PMID: 30817134.
Protein Function take part in molybdopterin biosynthesis and Cofactor biosynthesis.
Biochemical Properties  Binds 1 zinc ion per subunit.MOCS3 structurally and functionally resembles the ubiquitin-activating enzyme E1.The C-terminus of MOCS3 has a rhodanese-like fold and transfer sulfur to be transferred to MOCS2A(subunit of MPT synthase) in the form of a persulfide group.
PTMs Disulfide formation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Linking IDs
Bibliography Neukranz Y, Kotter A, Beilschmidt L, Marelja Z, Helm M, Gräf R, Leimkühler S. Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. Biochemistry. 2019 Apr 2;58(13):1786-1798. doi: 10.1021/acs.biochem.8b01160. Epub 2019 Mar 13. PMID: 30817134.