Search by BoMiProt ID - Bomi3700


Primary Information

BoMiProt ID Bomi3700
Protein Name Adenylosuccinate synthetase isozyme 1
Organism Bos taurus
Uniprot IdA5PJR4
Milk FractionExosomes
Ref Sequence Id NP_001092662.1
Aminoacid Length 457
Molecular Weight 50134
Fasta Sequence https://www.uniprot.org/uniprot/A5PJR4.fasta
Gene Name ADSS1
Gene Id 784089
Protein Existence Status reviewed

Secondary Information

Protein Function Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Biochemical Properties Cofactor is Mg2+.Utilises asparatate as substrate. Catalyses the following reaction-GTP + IMP + L-aspartate = GDP + 2 H+ + N6-(1,2-dicarboxyethyl)-AMP + phosphate.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions (1-25)
DisProt Annotation
TM Helix Prediction No TM helices