Search by BoMiProt ID - Bomi366


Primary Information

BoMiProt ID Bomi366
Protein Name Asparaginyl-tRNA synthetase, cytoplasmic
Organism Bos taurus
Uniprot IdQ2KJG3
Milk FractionExosome
Ref Sequence Id NP_001040037.1
Amino Acid Lenth 559
Molecular Weight 64399
Fasta Sequence https://www.uniprot.org/uniprot/Q2KJG3.fasta
Gene Name NARS
Gene Id 616033
Protein Existence Status Reviewed: Experimental evidence at transcript level

Secondry Information

Protein Function enzymes involved in protein biosynthesis catalyzing the specific attachment of amino acids to their cognate tRNAs;
Biochemical Properties classified as a sub-class IIb enzyme together with the aspartyl- and lysyl-enzymes on the basis of similarities in their N-terminal extensions and the catalytic domains; absence of a mitochondrial import signal
Significance in milk might play a part in tissue differentiation and regulation of mammary gland; individual tRNA's and aminoacyl-tRNA synthetases correspond to the amino acid composition of the main milk proteins
Bibliography 1. Beaulande, M., Tarbouriech, N. and Hartlein, M. (1998) ‘Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen’, Nucleic Acids Research, 26(2), pp. 521–524. doi: 10.1093/nar/26.2.521.
2. Cusack, S., Härtlein, M. and Leberman, R. (1991) ‘Sequence, structural and evolutionary relationships between class 2 aminoacyl-tRNA synthetases’, Nucleic Acids Research, 19(13), pp. 3489–3498. doi: 10.1093/nar/19.13.3489.