Search by BoMiProt ID - Bomi364


Primary Information

BoMiProt ID Bomi364
Protein Name Serine/threonine-protein kinase 10
Organism Bos taurus
Uniprot IdE1BK52
Milk FractionExosome
Aminoacid Length 966
Molecular Weight 111615
Fasta Sequence https://www.uniprot.org/uniprot/E1BK52.fasta
Gene Name STK10
Protein Existence Status Reviewed: Protein inferred from homology

Secondary Information

Protein Function Interact with diverse substrates ranging from enzymes, including other kinases, to transcription factors, receptors, and other regulatory proteins
Significance in milk Increase in protein supports milk protein synthesis during the periparturient period
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions 315-381,417-488,863-871,960-966
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1. Ma, Y. F. et al. (2019) ‘Phosphorylation of AKT serine/threonine kinase and abundance of milk protein synthesis gene networks in mammary tissue in response to supply of methionine in periparturient Holstein cows’, Journal of Dairy Science, 102(5), pp. 4264–4274. doi: 10.3168/jds.2018-15451.
2. Nerstedt, A. et al. (2012) ‘Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle’, Diabetologia, 55(6), pp. 1797–1807. doi: 10.1007/s00125-012-2511-7.
3. Kostich, M. et al. (2002) ‘Human members of the eukaryotic protein kinase family.’, Genome Biology, 3(9), p. research0043.1. doi: 10.1186/gb-2002-3-9-research0043.