Primary Information
BoMiProt ID	Bomi3483
Protein Name	2-hydroxyacyl-CoA lyase 2/Acetolactate synthase-like protein/IlvB-like protein
Organism	Bos taurus
Uniprot ID	A6QQT9
Milk Fraction	Whey
Ref Sequence ID	NP_001015535.1
Aminoacid Length	632
Molecular Weight	68110
FASTA Sequence	Download
Gene Name	ILVBL/AHAS/ HACL2
Gene ID	506955
Protein Existence Status	reviewed
Secondary Information
Protein Function	peroxisomal enzyme.the degradation of 3-methyl-branched fatty acids like phytanic acid and (ii) the shortening of 2-hydroxy long-chain fatty acids. splitting of a carbon-carbon bond between the first and second carbon atom in a 2-hydroxyacyl-CoA intermediate leading to the production of an (n-1) aldehyde and formyl-CoA.
Biochemical Properties	homotetramer and has a PTS (peroxisomal targeting signal) at the C-terminal side (PTS1).subunits of 63 kDa
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	1TMH;(11-33)
Bibliography	Casteels M, Sniekers M, Fraccascia P, Mannaerts GP, Van Veldhoven PP. The role of 2-hydroxyacyl-CoA lyase, a thiamin pyrophosphate-dependent enzyme, in the peroxisomal metabolism of 3-methyl-branched fatty acids and 2-hydroxy straight-chain fatty acids. Biochem Soc Trans. 2007 Nov;35(Pt 5):876-80. doi: 10.1042/BST0350876. PMID: 17956236.