Primary Information
BoMiProt ID	Bomi347
Protein Name	Ribosome maturation protein SBDS
Organism	Bos taurus
Uniprot ID	Q3SWZ6
Milk Fraction	Exosome
Ref Sequence ID	NP_001029611.1
Aminoacid Length	250
Molecular Weight	28718
FASTA Sequence	Download
Gene Name	SBDS
Gene ID	513237
Protein Existence Status	Reviewed: Experimental evidence at transcript level
Secondary Information
Presence in other biological fluids/tissue/cells	Human SBDS is enriched in the nucleolus
Protein Function	SBDS forms a protein complex with nucleophosmin; involved in RNA metabolism or translation; required in ribosome biosynthesis
Biochemical Properties	Cosediments with the large 60S ribosomal subunit in sucrose gradients; associates with 28S rRNA
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1. Vasieva, O. (2011) ‘Role of Shwachman-Bodian-Diamond syndrome protein in translation machinery and cell chemotaxis: a comparative genomics approach’, Advances and Applications in Bioinformatics and Chemistry, 4, p. 43. doi: 10.2147/AABC.S23510. 2. Ganapathi, K. A. et al. (2007) ‘The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNA’, Blood, 110(5), pp. 1458–1465. doi: 10.1182/blood-2007-02-075184. 3. Shammas, C. et al. (2005) ‘Structural and Mutational Analysis of the SBDS Protein Family’, Journal of Biological Chemistry, 280(19), pp. 19221–19229. doi: 10.1074/jbc.M414656200.