Search by BoMiProt ID - Bomi3467


Primary Information

BoMiProt ID Bomi3467
Protein Name 26S proteasome non-ATPase regulatory subunit 13/26S proteasome regulatory subunit RPN9/26S proteasome regulatory subunit S11
Organism Bos taurus
Uniprot IdQ5E964
Milk FractionExosomes
Ref Sequence Id NP_001019703.1
Aminoacid Length 376
Molecular Weight 42866
Fasta Sequence https://www.uniprot.org/uniprot/Q5E964.fasta
Gene Name PSMD13
Gene Id 513525
Protein Existence Status Reviewed

Secondary Information

Protein Function Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.
Biochemical Properties Contains 20S core particle (CP) and two 19S regulatory subunits (RP).The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions (1-12)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Takeuchi, J., Fujimuro, M., Yokosawa, H., Tanaka, K., & Toh-e, A. (1999). Rpn9 is required for efficient assembly of the yeast 26S proteasome. Molecular and cellular biology, 19(10), 6575–6584. https://doi.org/10.1128/MCB.19.10.6575