Search by BoMiProt ID - Bomi328


Primary Information

BoMiProt ID Bomi328
Protein Name Solute carrier family 22 (Organic cation/carnitine transporter), member 5
Organism Bos taurus
Uniprot IdQ2KJE9
Milk FractionExosome
Ref Sequence Id NP_001039967.1
Aminoacid Length 557
Molecular Weight 62826
Fasta Sequence https://www.uniprot.org/uniprot/Q2KJE9.fasta
Gene Name SLC22A5
Gene Id 541266
Protein Existence Status Unreviewed: Experimental evidence at transcript level

Secondary Information

Presence in other biological fluids/tissue/cells present in kidney and liver, brain, placenta, intestine, and lung
Protein Function operate as transporters for organic cations (OCTs), organic cations and zwitterions (OCTNs) or organic anions; play a pivotal role in the secretion of organic ions; contribute to the homeostasis of organic ions; polyspecific transporters as they are able to transport structurally different compounds
Significance in milk nutrient transport systems for milk precursors and constituents
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Bibliography 1. Anzai, N., Jutabha, P., Enomoto, A., Yokoyama, H., Nonoguchi, H., Hirata, T., … Endou, H. (2005). Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules. The Journal of Pharmacology and Experimental Therapeutics, 315(2), 534–544. https://doi.org/10.1124/jpet.105.088583.
2. Jacobsson, J. A., Haitina, T., Lindblom, J., & Fredriksson, R. (2007). Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Genomics, 90(5), 595–609. https://doi.org/10.1016/j.ygeno.2007.03.017.