Search by BoMiProt ID - Bomi3142


Primary Information

BoMiProt ID Bomi3142
Protein Name Afamin
Organism Bos taurus
Uniprot IDG3MYZ3
Milk FractionWhey
Ref Sequence ID NP_001179104.1
Aminoacid Length 604
Molecular Weight 69562
FASTA Sequence Download
Gene Name AFM
Gene ID 508264
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondary Information

Protein Function Afamin plays a role in anti-apoptotic cellular processes related to oxidative stress and is associated with insulin resistance and other features of metabolic syndrome. 
PTMs N-glycosylated at Asn; more than 90% of the glycans are sialylated,Disulfide bond formation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions 597-604
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Köninger A, Mathan A, Mach P, Frank M, Schmidt B, Schleussner E, Kimmig R, Gellhaus A, Dieplinger H. Is Afamin a novel biomarker for gestational diabetes mellitus? A pilot study. Reprod Biol Endocrinol. 2018 Mar 27;16(1):30. doi: 10.1186/s12958-018-0338-x. PMID: 29587878; PMCID: PMC5870691.