Search by BoMiProt ID - Bomi291

Primary Information

BoMiProt ID Bomi291
Protein Name Heat shock protein 105 kDa
Organism Bos taurus
Uniprot IdQ0IIM3
Milk FractionMFGM, Exosome
Ref Sequence Id NP_001068770.1
Amino Acid Lenth 859
Molecular Weight 96726
Fasta Sequence
Gene Name HSPH1
Gene Id 507165
Protein Existence Status Reviewed: Experimental evidence at transcript level

Secondry Information

Presence in other biological fluids/tissue/cells 105-kDa heat-shock protein (HSP105) as a mammalian high molecular mass heat-shock protein in human, mouse, and rat cells; moderately expressed in adrenal, spleen, liver, lung, and heart; Small amounts of HSP105 are expressed in the kidney, stomach, muscle, testis, and lens. However, in brain HSP105-a was characteristically highly expressed over HSP105-b
Protein Function induced in various tissues of rat after whole-body hyperthermia; HSP105 level of HSP10S increased markedly in the embryos from gestational day (GD) 9 to 11, then decreased gradually by GD 14; plays important roles in mouse embryogenesis; prevent the aggregation of heat-denatured proteins in vitro;
Biochemical Properties HSPI05 is composed of two isoforms with slightly different isoelectric points with slightly different isoelectric points, acidic and basic isoforms; mRNA was also induced by azetidine-2-carboxylic acid, sodium arsenite, zinc sulfate, and cupric sulfate;
Significance in milk heat stress proteins in mamary gland
Significance of PTMs sensitive to heat stress and mainly responsible for mammary cell protection from heat stress
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