Primary Information |
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BoMiProt ID | Bomi2788 |
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Protein Name | Tuftelin-interacting protein 11 |
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Organism | Bos taurus |
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Uniprot ID | Q29RR5 |
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Milk Fraction | Exosome |
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Ref Sequence ID | NP_001039495.2 |
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Aminoacid Length | 837 |
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Molecular Weight | 96085 |
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FASTA Sequence |
Download |
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Gene Name | TFIP11 |
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Gene ID | 509349 |
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Protein Existence Status | Reveiwed:Experimental evidence at transcript level |
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Secondary Information |
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Protein Function | Tuftelin-interacting protein 11 (TFIP11) is a protein component of the spliceosome complex that promotes the release of the lariat-intron during late-stage splicing through a direct recruitment and interaction with DHX15/PRP43. |
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PTMs | Phosphorylation at serine |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
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Predicted Disorder Regions | 1-31,54-73,85-136,183-236,287-313 |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Bibliography | Tannukit S, Crabb TL, Hertel KJ, Wen X, Jans DA, Paine ML. Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly. Biochem Biophys Res Commun. 2009 Dec 18;390(3):1044-50. doi: 10.1016/j.bbrc.2009.10.111. Epub 2009 Oct 24. PMID: 19857462; PMCID: PMC2787706. |