Search by BoMiProt ID - Bomi2788


Primary Information

BoMiProt ID Bomi2788
Protein Name Tuftelin-interacting protein 11
Organism Bos taurus
Uniprot IDQ29RR5
Milk FractionExosome
Ref Sequence ID NP_001039495.2
Aminoacid Length 837
Molecular Weight 96085
FASTA Sequence Download
Gene Name TFIP11
Gene ID 509349
Protein Existence Status Reveiwed:Experimental evidence at transcript level

Secondary Information

Protein Function Tuftelin-interacting protein 11 (TFIP11) is a protein component of the spliceosome complex that promotes the release of the lariat-intron during late-stage splicing through a direct recruitment and interaction with DHX15/PRP43. 
PTMs Phosphorylation at serine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions 1-31,54-73,85-136,183-236,287-313
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Tannukit S, Crabb TL, Hertel KJ, Wen X, Jans DA, Paine ML. Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly. Biochem Biophys Res Commun. 2009 Dec 18;390(3):1044-50. doi: 10.1016/j.bbrc.2009.10.111. Epub 2009 Oct 24. PMID: 19857462; PMCID: PMC2787706.