Primary Information |
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BoMiProt ID | Bomi277 |
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Protein Name | Uroporphyrinogen decarboxylase |
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Organism | Bos taurus |
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Uniprot ID | E1BEX4 |
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Milk Fraction | Exosome |
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Ref Sequence ID | NP_001192487.1 |
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Aminoacid Length | 367 |
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Molecular Weight | 40812 |
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FASTA Sequence |
Download |
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Gene Name | UROD |
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Gene ID | 504914 |
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Protein Existence Status | Unreviewed: Protein inferred from homology |
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Secondary Information |
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Protein Function | Converts uroporphyrinogen I or III into coproporphyrinogen
I or III, respectively |
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Biochemical Properties | Uroporphyrinogen decarboxylase
is dimeric in form; purified enzyme had an
isoelectric point of 6.2 and a pH optimum of 6.8; specific inhibitors - 3,4,3’,4’-Tetrachlorobiphenyl
and 3,4,5,3’,4’,5’-hexachlorobiphenyl |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
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Bibliography | 1. Kawanishi, S., Seki, Y. and Sano, S. (1983) ‘Uroporphyrinogen decarboxylase. Purification, properties, and inhibition by polychlorinated biphenyl isomers.’, The Journal of biological chemistry, 258(7), pp. 4285–92. Available at: http://www.ncbi.nlm.nih.gov/pubmed/6403526 (Accessed: 4 October 2019). |