Search by BoMiProt ID - Bomi2745


Primary Information

BoMiProt ID Bomi2745
Protein Name SNW domain-containing protein 1
Organism Bos taurus
Uniprot IDQ1JQE0
Milk FractionExosome
Ref Sequence ID NP_001071302.1
Aminoacid Length 536
Molecular Weight 61505
FASTA Sequence Download
Gene Name SNW1
Gene ID 326578
Protein Existence Status Reveiwed:Experimental evidence at transcript level

Secondary Information

Protein Function The SNW1 protein is functionally characterized as a spliceosome component as well as a transcriptional coregulator
Biochemical Properties Bx42 and its homologs contain a SNW/SKIP domain with an S–N–W–K–N peptide signature and are evolutionarily well-conserved protein among different species.
PTMs N-acetylation at Alanine,Isopeptide bond formation, Phosphorylation at Ser,Ubl conjugation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions 1-46,59-129,209-233,311-386,472-536
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Xu L, Zhou X, Wu Y, Yang J, Xu H. A novel SNW/SKIP domain-containing protein, Bx42, is involved in the antibacterial responses of Macrobrachium nipponense. Dev Comp Immunol. 2020 Dec;113:103788. doi: 10.1016/j.dci.2020.103788. Epub 2020 Jul 18. PMID: 32692995. 2.J.D. Figueroa, M.J. Hayman.Differential effects of the Ski-interacting protein (SKIP) on differentiation induced by transforming growth factor-β1 and bone morphogenetic protein-2 in C2C12 cells.Exp. Cell Res., 296 (2004), pp. 163-172, 10.1016/j.yexcr.2004.01.025. 3.G.M. Leong, N. Subramaniam, L.L. Issa, J.B. Barry, T. Kino, P.H. Driggers, M.J. Hayman, J.A. Eisman, E.M. Gardiner.Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300.Biochem. Biophys. Res. Commun., 315 (2004), pp. 1070-1076, 10.1016/j.bbrc.2004.02.004. 4.P. Folk, F. Půta, L. Krpejšová, A. Blahůšková, A. Markoš, M. Rabino, R.P. Dottin.The homolog of chromatin binding protein Bx42 identified in Dictyostelium Gene, 181 (1996), pp. 229-231, 10.1016/S0378-1119(96)00483-0. 5.M. Hong, J. He, S. Li.SNW1 regulates Notch signaling in neuroblastoma through interacting with RBPJ.Biochem. Biophys. Res. Commun., 509 (2019), pp. 869-876, 10.1016/j.bbrc.2019.01.036.