Primary Information
BoMiProt ID	Bomi2743
Protein Name	Gamma-soluble NSF attachment protein
Organism	Bos taurus
Uniprot ID	P81127
Milk Fraction	MFGM, Exosome
Ref Sequence ID	NP_001039487.1
Aminoacid Length	312
Molecular Weight	34636
FASTA Sequence	Download
Gene Name	NAPG
Gene ID	509041
Protein Existence Status	Reviewed: Experimental evidence at protein level
Secondary Information
Protein Function	gamma-Soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (gamma-SNAP) is capable of stabilizing a 20 S complex consisting of NSF, alpha-SNAP, and SNAP receptors (SNAREs)
Biochemical Properties	The SNAP family consists of ubiquitously expressed and isoforms and a brain-specific isoform. So far alpha-SNAP has been studied most extensively. alpha-SNAP stimulates the ATPase activity of NSF by interacting via its N-terminal and extreme C-terminal regions and is essential for a wide variety of membrane fusion events including intra-Golgi protein transport.
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation
Predicted Disorder Regions	(281-312)
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Tani K, Shibata M, Kawase K, Kawashima H, Hatsuzawa K, Nagahama M, Tagaya M. Mapping of functional domains of gamma-SNAP. J Biol Chem. 2003 Apr 11;278(15):13531-8. doi: 10.1074/jbc.M213205200. Epub 2003 Jan 27. PMID: 12554740. 2.Morgan, A., Dimaline, R., and Burgoyne, R. D. (1994) J. Biol. Chem. 269,29347–29350. 3.Barnard, R. J. O., Morgan, A., and Burgoyne, R. D. (1997) J. Cell Biol. 139,875–883. 4.Clary, D. O., Griff, I. C., and Rothman, J. E. (1990) Cell 61, 709–721