Primary Information |
|---|
| BoMiProt ID | Bomi2727 |
|---|
| Protein Name | Calcium-binding mitochondrial carrier protein SCaMC-1 |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | A5PJZ1 |
|---|
| Milk Fraction | MFGM |
|---|
| Ref Sequence ID | NP_001092536.1 |
|---|
| Aminoacid Length | 477 |
|---|
| Molecular Weight | 53285 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | SLC25A24 |
|---|
| Gene ID | 534742 |
|---|
| Protein Existence Status | Reveiwed:Experimental evidence at transcript level |
|---|
Secondary Information |
|---|
| Biochemical Properties | Mitochondrial carriers (MC) form a highly conserved family involved in solute transport across the inner mitochondrial membrane in eukaryotes. In mammals, ATP-Mg/Pi carriers, SCaMCs, form the most complex subgroup with four paralogs, SCaMC-1, -2, -3 and -3L, and several splicing variants. |
|---|
| PTMs | N6-acetylation at Lysine |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| |
|---|
| Predicted Disorder Regions | 50-78, 99-109, 159-170 |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
| Additional Comments | In mouse, SCaMC-1L expression is restricted to male germ cells and regulated during spermatogenesis but unexpectedly its localization is not limited to mitochondrial structures. |
|---|
| Bibliography | 1.Amigo I, Traba J, Satrústegui J, del Arco A. SCaMC-1Like a member of the mitochondrial carrier (MC) family preferentially expressed in testis and localized in mitochondria and chromatoid body. PLoS One. 2012;7(7):e40470. doi: 10.1371/journal.pone.0040470. Epub 2012 Jul 6. PMID: 22792342; PMCID: PMC3391283. 2.Amigo I, Traba J, Satrústegui J, del Arco A. SCaMC-1Like a member of the mitochondrial carrier (MC) family preferentially expressed in testis and localized in mitochondria and chromatoid body. PLoS One. 2012;7(7):e40470. doi: 10.1371/journal.pone.0040470. Epub 2012 Jul 6. PMID: 22792342; PMCID: PMC3391283. |
|---|
