Search by BoMiProt ID - Bomi270


Primary Information

BoMiProt ID Bomi270
Protein Name Beta Defensin 10
Organism Bos taurus
Uniprot IdP46168
Milk FractionMFGM
Ref Sequence Id NP_001108556.1
Amino Acid Lenth 62
Molecular Weight 6928
Fasta Sequence https://www.uniprot.org/uniprot/P46168.fasta
Gene Name DEFB10
Gene Id 100141457
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondry Information

Protein Function amphipathic cationic peptides that have been reported to function as AMPs for the Gramnegative, Gram-positive bacteria, viruses, fungi, and other unicellular parasites; confer resistance against mastitis in cattle and buffalo next to the TLRs;
Biochemical Properties cationic and cysteine-rich AMP displaying a varied pattern of cysteine spacing and disulfide bonding between cysteine residues;
Significance in milk higher in early lactation stages than in the later stages on infection by coagulase-positive Staphylococci
Bibliography 1. Birchler, T. et al. (2001) ‘Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein.’, European journal of immunology, 31(11), pp. 3131–7. doi: 10.1002/1521-4141(200111)31:11<3131::AID-IMMU3131gt;3.0.CO;2-G.