Search by BoMiProt ID - Bomi255


Primary Information

BoMiProt ID Bomi255
Protein Name Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Organism Bos taurus
Uniprot IdP00423
Milk FractionMFGM
Ref Sequence Id NP_001001439.1
Amino Acid Lenth 169
Molecular Weight 19572
Fasta Sequence https://www.uniprot.org/uniprot/P00423.fasta
Gene Name COX4I1
Gene Id 281090
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondry Information

Protein Function terminal enzyme of the respiratory chains of mitochondria; use the electrons of cytochrome c to reduce molecular oxygen; central role in aerobic metabolism- participates in respiratory control
Biochemical Properties members of the superfamily of heme/copper containing terminal oxidases;
PTMs phoshorylated
Significance of PTMs activity can be modulated according to the energetic requirement of the cell through isoform subunits composition and physiologically controlled phosphorylation
PDB ID 1OCC, 1OCO, 1OCR, 1OCZ, 1V54, 1V55, 2DYR, 2DYS, 2EIJ, 2EIK, 2EIL, 2EIM, 2EIN, 2OCC, 2Y69, 2YBB, 2ZXW, 3ABK, 3ABL, 3ABM, 3AG1, 3AG2, 3AG3, 3AG4, 3ASN, 3ASO, 3WG7, 3X2Q, 5B1A, 5B1B, 5GPN, 5IY5, 5LUF, 5W97, 5WAU, 5X19, 5X1B, 5X1F, 5XDQ, 5XDX, 5XTH, 5XTI, 5Z84, 5Z85, 5Z86, 5ZCO, 5ZCP, 5ZCQ, 6NKN, 6NMF, 6NMP ,
Bibliography 1. Zong, S. et al. (2018) ‘Structure of the intact 14-subunit human cytochrome c oxidase.’, Cell research, 28(10), pp. 1026–1034. doi: 10.1038/s41422-018-0071-1.
2. Tsukihara, T. et al. (1996) ‘The Whole Structure of the 13-Subunit Oxidized Cytochrome c Oxidase at 2.8 A’, Science, 272(5265), pp. 1136–1144. doi: 10.1126/science.272.5265.1136.
3. Linder, D., Freund, R. and Kadenbach, B. (1995) ‘Species-specific expression of cytochrome c oxidase isozymes’, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 112(3), pp. 461–469. doi: 10.1016/0305-0491(95)00093-3.