Primary Information |
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BoMiProt ID | Bomi2283 |
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Protein Name | Hydroxyacylglutathione hydrolase, mitochondrial |
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Organism | Bos taurus |
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Uniprot ID | Q3B7M2 |
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Milk Fraction | Exosome |
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Ref Sequence ID | NP_001030351.1 |
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Aminoacid Length | 308 |
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Molecular Weight | 34089 |
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FASTA Sequence |
Download |
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Gene Name | HAGH |
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Gene ID | 509274 |
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Protein Existence Status | Reviewed: Experimental evidence at transcript level |
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Secondary Information |
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Protein Function | It involves direct nucleophilic attack of an active-site histidine on the thiol ester substrate to form an acyl-imidazole intermediate which then rapidly hydrolyses. |
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PTMs | N6-acetylation at Lysine |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
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Predicted Disorder Regions | NA |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Bibliography | 1.Vander Jagt DL. Glyoxalase II: molecular characteristics, kinetics and mechanism. Biochem Soc Trans. 1993 May;21(2):522-7. doi: 10.1042/bst0210522. PMID: 8359524. |