Search by BoMiProt ID - Bomi214


Primary Information

BoMiProt ID Bomi214
Protein Name Cytosol aminopeptidase
Organism Bos taurus
Uniprot IdP00727
Milk FractionExosome
Ref Sequence Id NP_776523.2
Amino Acid Lenth 519
Molecular Weight 56289
Fasta Sequence https://www.uniprot.org/uniprot/P00727.fasta
Gene Name LAP3
Gene Id 781648
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondry Information

Protein Function catalyze the rapid hydrolysis of aminoacyl-/3-naphthylamides;
Biochemical Properties broader specificity while hydrolyzing Leu substrates; have variable temperature and pH optima and divalent cation requirements;
Significance in milk show high potential in removing the bitterness of milk by hydrolysis of polypeptides
PDB ID 1BLL, 1BPM, 1BPN, 1LAM, 1LAN, 1LAP, 1LCP, 2EWB, 2J9A,
Bibliography 1. TALANTI, S., & HOPSU, V. K. (1961). Leucine aminopeptidase in the mammary gland of the cow and rat. Nature, 191, 86–87. https://doi.org/10.1038/191086b0.
2. Jóźwik, A., Bagnicka, E., Śliwa-Jóźwik, A., Strzałkowska, N., Sloniewski, K., Krzyżewski, J., & Kolataj, A. (2004). Activity of selected aminopeptidases of whole milk in cows as related to feeding season (autumn/winter vs spring/summer)..
3. Starnes, W. L., & Behal, F. J. (1974). A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein. Biochemistry, 13(16), 3221–3227. https://doi.org/10.1021/bi00713a004.