Unreviewed: Experimental evidence at transcript level
Secondary Information
Protein Function
Induce GTPase activity via hydrolysis of E-site GTP in the native tubulin heterodimer; in recruitment of the γ-tubulin ring complex
at centrosomes and organization of the mitotic spindle; central to the pathway leading to the de novo assembly of the tubulin
heterodimer; disrupts tubulin and microtubule integrity upon
overexpression
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
Bibliography
1. Tian, G., Thomas, S., & Cowan, N. J. (2010). Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity. Cytoskeleton (Hoboken, N.J.), 67(11), 706–714. https://doi.org/10.1002/cm.20480.