Search by BoMiProt ID - Bomi198


Primary Information

BoMiProt ID Bomi198
Protein Name TBCD protein
Organism Bos taurus
Uniprot IDA7MB50
Milk FractionExosome
Aminoacid Length 1172
Molecular Weight 129966
FASTA Sequence Download
Gene Name TBCD
Protein Existence Status Unreviewed: Experimental evidence at transcript level

Secondary Information

Protein Function Induce GTPase activity via hydrolysis of E-site GTP in the native tubulin heterodimer; in recruitment of the γ-tubulin ring complex at centrosomes and organization of the mitotic spindle; central to the pathway leading to the de novo assembly of the tubulin heterodimer; disrupts tubulin and microtubule integrity upon overexpression
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Bibliography 1. Tian, G., Thomas, S., & Cowan, N. J. (2010). Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity. Cytoskeleton (Hoboken, N.J.), 67(11), 706–714. https://doi.org/10.1002/cm.20480.