Protein Function | might have flexible cell-type-specific roles, forming unique
scaffolds that are dependent on the available intracellular
environment; at least ten putative binding PDZ2 tandem, but neither the isolated domains nor
partners reported for syntenin , including IL-5 receptor α-subunit, neuroglian, pro-TGFα |
---|
Bibliography | 1. Kang, B. S., Cooper, D. R., Jelen, F., Devedjiev, Y., Derewenda, U., Dauter, Z., Otlewski, J., and Derewenda, Z. S. (2003) PDZ tandem of human syntenin: crystal structure and functional properties. Structure 11, 459–468. 2. Grootjans, J. J., Zimmermann, P., Reekmans, G., Smets, A., Degeest, G., Dürr, J., and David, G. (1997) Syntenin, a PDZ protein that binds syndecan cytoplasmic domains. Proc. Natl. Acad. Sci. U. S. A. 94, 13683–13688. 3. Koroll, M., Rathjen, F. G., and Volkmer, H. (2001) The Neural Cell Recognition Molecule Neurofascin Interacts with Syntenin-1 but Not with Syntenin-2, Both of Which Reveal Self-associating Activity. J. Biol. Chem. 276, 10646–10654. |