Search by BoMiProt ID - Bomi143


Primary Information

BoMiProt ID Bomi143
Protein Name Carboxypeptidase B2
Organism Bos taurus
Uniprot IdQ2KIG3
Milk FractionWhey
Ref Sequence Id NP_001039462.1
Amino Acid Lenth 423
Molecular Weight 48822
Fasta Sequence https://www.uniprot.org/uniprot/Q2KIG3.fasta
Gene Name CPB2
Gene Id 508222
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondry Information

Protein Function enzyme that selectively catalyzes the release of the carboxyl-terminal basic amino acids, arginine and lysine, from proteins and peptides; possess esterase activity toward hippuryl-n-argininic acid
Biochemical Properties The inhibition of the enzyme by phosphate and that by citrate are pH-dependent and are most pronounced below pH 6.5; decreasing effectiveness as inhibitors at pH 8: NaI, KSCN, NaBr, MgS04, NaCI, KCl, and NaN03;
Significance in milk belong to the protease system in milk
PDB ID 3D4U, 3DGV, 3OSL,
Bibliography 1. FOLK, J. E., WOLFF, E. C., & SCHIRMER, E. W. (1962). The kinetics of carboxypeptidase B activity. II. Kinetic parameters of the cobalt and cadmium enzymes. The Journal of Biological Chemistry, 237, 3100–3104. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/13945772