Search by BoMiProt ID - Bomi1294


Primary Information

BoMiProt ID Bomi1294
Protein Name Protein FAM115C
Organism Bos taurus
Uniprot IDA6QLU7
Milk FractionExosome
Ref Sequence ID NP_001095394.1
Aminoacid Length 914
Molecular Weight 99893
FASTA Sequence Download
Gene Name TCAF2
Gene ID 510320
Protein Existence Status Reveiwed:Experimental evidence at transcript level

Secondary Information

Protein Function TRP channel-associated factor 1/2 (TCAF1/TCAF2) proteins antagonistically regulate the cold-sensor protein TRPM8 in multiple human tissues.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Hsieh P, Dang V, Vollger MR, Mao Y, Huang TH, Dishuck PC, Baker C, Cantsilieris S, Lewis AP, Munson KM, Sorensen M, Welch AE, Underwood JG, Eichler EE. Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans. Nat Commun. 2021 Aug 25;12(1):5118. doi: 10.1038/s41467-021-25435-4. PMID: 34433829; PMCID: PMC8387397.