Search by BoMiProt ID - Bomi10776


Primary Information

BoMiProt ID Bomi10776
Protein Name Zinc finger protein 692/AICAR responsive element binding protein
Organism Bos taurus
Uniprot IDA0JNJ4
Milk FractionWhey
Ref Sequence ID NP_001019667.2
Aminoacid Length 510
Molecular Weight 55474
FASTA Sequence Download
Gene Name ZNF692/AREBP
Gene ID 507847
Protein Existence Status reviewed

Secondary Information

Protein Function It may act as an transcriptional repressor for PCK1 gene expression. It may also be involved in AMPK signaling pathway for regulation of hepatic gluconeogenesis.
PTMs Phosphorylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|A0JNJ4|ZN692_BOVIN Zinc finger protein 692 OS=Bos taurus OX=9913 GN=ZNF692 PE=2 SV=1 MAASPADASRRRREKRRQLDARRSKCRIRLGGHMEQWCLLKEQLGFSLHSQLAKFLLDRY TSSGCVLCAGPEPVAPKGLQYLVLLSHAHSRECSLVPGLRGPGGQDGGLVWECSAGHTFS WGPSSGPKSPEEPNLTPLPSTDERSWCPEAKSGQEPAGLES*161NCDERAQEARMPRGAGPPP ETFPSLGEDGEEEEEDEEEMLSDASPWTYSSSPDDEPDVPKPPPS*225PVTHALKDGEIAPAP AAVPAPLASPSSSASSLGSGAPGPVEVRIQPELRGTPQADQQTEPLASPGSQAQSALASA WDEDTAQIGPKRIRKAAKRELLPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFSCPEPAC GKSFNFKKHLKEHVKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTC RQKASLNWHRRKHAETVAALRFPCEFCGKRFEKPDSVAAHRSKS*464HPALLLAPQELSGPVE SCSSILASASLGASEGSRSTLAPQAPILLP
Predicted Disorder Regions (1-19), (94-104), (119-250), (260-300)
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs Phosphorylation at Ser-464 results in loss of DNA-binding activity.
Bibliography Xing, Y., Ren, S., Ai, L., Sun, W., Zhao, Z., Jiang, F., Zhu, Y., & Piao, D. (2019). ZNF692 promotes colon adenocarcinoma cell growth and metastasis by activating the PI3K/AKT pathway. International journal of oncology, 54(5), 1691–1703. https://doi.org/10.3892/ijo.2019.4733