Primary Information |
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| BoMiProt ID | Bomi10649 |
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| Protein Name | YTH domain-containing family protein 2 |
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| Organism | Bos taurus |
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| Uniprot ID | Q0VCZ3 |
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| Milk Fraction | whey |
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| Ref Sequence ID | NP_001069721.1 |
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| Aminoacid Length | 580 |
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| Molecular Weight | 62449 |
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| FASTA Sequence |
Download |
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| Gene Name | YTHDF2 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | role in cell proliferation, invasion, and cholesterol regulation ,regulation of neurogenesis |
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| PTMs | phosphorylation on Ser,Acetylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q0VCZ3|YTHD2_BOVIN YTH domain-containing family protein 2 OS=Bos taurus OX=9913 GN=YTHDF2 PE=2 SV=1
MS*2AS*4S*5LLEQRPKGQGNKVQNGS*22VHQKDGLNDDDFEPYLS*39PQARPNNAYTAMSDSYLPSYY
SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFASETLNKAP
GMNTIDQGMAALKLGS*196TEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQQP
TQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGS*360
GFGHNGVDGNGVGQTQAGSGSTPSEPHPVLEKLRS*395INNYNPKDFDWNLKHGRVFIIKSYS
EDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDY
NTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQ
VLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Significance of PTMs | EGFR/SRC/ERK signaling phosphorylates YTHDF2 serine39 and threonine381, stabilizing YTHDF2 protein. |
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