Search by BoMiProt ID - Bomi10486


Primary Information

BoMiProt ID Bomi10486
Protein Name Visual system homeobox 1/Homeodomain protein RINX/Retinal inner nuclear layer homeobox protein/Transcription factor VSX1
Organism Bos taurus
Uniprot IdQ9GMA3
Milk FractionWhey
Ref Sequence Id NP_777192.1
Aminoacid Length 365
Molecular Weight 38526
Fasta Sequence https://www.uniprot.org/uniprot/Q9GMA3.fasta
Gene Name VSX1/RINX
Gene Id 286802
Protein Existence Status reviewed

Secondary Information

Protein Function ocular development.Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster.May regulate the activity of the LCR and the cone opsin genes at earlier stages of development.
Biochemical Properties VSX1 gene forms part of a paired-like homeodomain transcription factor which is responsible for ocular development.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 2-171, 279-365
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Ng JB, Poh RY, Lee KR, Subrayan V, Deva JP, Lau AY, Tan JA. Visual System Homeobox 1 (VSX1) Gene Analysis in Keratoconus: Design of Specific Primers and DNA Amplification Protocols for Accurate Molecular Characterization. Clin Lab. 2016 Sep 1;62(9):1731-1737. doi: 10.7754/Clin.Lab.2016.160144. PMID: 28164597.