Search by BoMiProt ID - Bomi10261


Primary Information

BoMiProt ID Bomi10261
Protein Name Ubiquitin-conjugating enzyme E2 G2/E2 ubiquitin-conjugating enzyme G2/Ubiquitin-protein ligase G2
Organism Bos taurus
Uniprot IdQ17QG5
Milk FractionExosomes
Ref Sequence Id NP_001069796.1
Aminoacid Length 165
Molecular Weight 18552
Fasta Sequence https://www.uniprot.org/uniprot/Q17QG5.fasta
Gene Name UBE2G2
Gene Id 614471
Protein Existence Status Reviewed

Secondary Information

Protein Function The human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) is involved in protein degradation, including a process known as endoplasmic reticulum-associated degradation (ERAD).
Biochemical Properties UBE2G2 comprises a single domain consisting of an antiparallel β-sheet with four strands (β1–β4), five α-­helices (α1–α5) and two 310-helices (η1 and η2).UBE2G2 has the extra long loop (LL) region (95–106), which is probably located on the side near the RING domain.
PTMs N-acetylation at Ala
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Arai R, Yoshikawa S, Murayama K, Imai Y, Takahashi R, Shirouzu M, Yokoyama S. Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Apr 1;62(Pt 4):330-4. doi: 10.1107/S1744309106009006. Epub 2006 Mar 25. PMID: 16582478; PMCID: PMC2222581. 2.