Search by BoMiProt ID - Bomi10188


Primary Information

BoMiProt ID Bomi10188
Protein Name U3 small nucleolar RNA-associated protein 15 homolog
Organism Bos taurus
Uniprot IdA7MB12
Milk FractionWhey
Ref Sequence Id /NP_001094598.1
Aminoacid Length 519
Molecular Weight 58495
Fasta Sequence https://www.uniprot.org/uniprot/A7MB12.fasta
Gene Name UTP15
Gene Id 526343
Protein Existence Status reviewed

Secondary Information

Protein Function WD-repeat containing proteins in human SSU processome components.The SSU processome is a 2.2 MDa ribonucleoprotein complex involved in not only the processing of rRNA but also the assembly and maturation of the SSU of eukaryotic ribosomes.Participate in nucleolar processing of pre-18S ribosomal RNA.
Biochemical Properties WD-repeats are conserved domains comprising approximately 40–60 amino acids and forms a beta propeller conformation.WD-repeats act as structural platforms for protein–protein interactions.
PTMs Acetylation, Isopeptide bond formation, Ubl conjugation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction no TM helices
Additional Comments found in the nuclear matrix fraction of HeLa cells
Bibliography Wada K, Sato M, Araki N, Kumeta M, Hirai Y, Takeyasu K, Furukawa K, Horigome T. Dynamics of WD-repeat containing proteins in SSU processome components. Biochem Cell Biol. 2014 Jun;92(3):191-9. doi: 10.1139/bcb-2014-0007. Epub 2014 Mar 27. PMID: 24754225.