Search by BoMiProt ID - Bomi10184


Primary Information

BoMiProt ID Bomi10184
Protein Name U1 small nuclear ribonucleoprotein 70 kDa/U1 snRNP 70 kDa/U1-70K/snRNP70
Organism Bos taurus
Uniprot IDQ1RMR2
Milk FractionWhey
Ref Sequence ID NP_001069514.1
Aminoacid Length 439
Molecular Weight 51426
FASTA Sequence Download
Gene Name SNRNP70/SNRP70
Gene ID 535113
Protein Existence Status reviewed

Secondary Information

Protein Function It is a component of the spliceosomal U1 snRNP and is crucial for pre-mRNA 5' splice-site recognition followed by spliceosome assembly.
PTMs Phosphorylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|Q1RMR2|RU17_BOVIN U1 small nuclear ribonucleoprotein 70 kDa OS=Bos taurus OX=9913 GN=SNRNP70 PE=2 SV=1 MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRA ETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLR REFEVY*126GPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVER GRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPS*226PLPHRDRDRDRERE RRERSRERDKERERRRSRSRDRRRRSRS*268RDKEERRRSRERSKDKDRDRKRRSSRSRERAR RERERKEELRGGGGGGGDMAEPS*323EAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRDRRRS HRSERERRRDRDRDRDREHKRGERGGDRGRDEARGGGGGGQDNGLEGLGNDGRDMYMESE GGDGYLAPENGYLMEAAPE
Predicted Disorder Regions (20-31), (46-97), (207-438)
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs Extensively phosphorylated on serine residues in the C-terminal region
Bibliography Yin, Y., Lu, J. Y., Zhang, X., Shao, W., Xu, Y., Li, P., Hong, Y., Cui, L., Shan, G., Tian, B., Zhang, Q. C., & Shen, X. (2020). U1 snRNP regulates chromatin retention of noncoding RNAs. Nature, 580(7801), 147–150. https://doi.org/10.1038/s41586-020-2105-3