Search by BoMiProt ID - Bomi10142


Primary Information

BoMiProt ID Bomi10142
Protein Name Tumor necrosis factor alpha-induced protein 8
Organism Bos taurus
Uniprot IdA4IF78
Milk FractionExosomes
Ref Sequence Id NP_001077180.1
Aminoacid Length 198
Molecular Weight 22995
Fasta Sequence https://www.uniprot.org/uniprot/A4IF78.fasta
Gene Name TNFAIP8
Gene Id 529336
Protein Existence Status reviewed

Secondary Information

Protein Function Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 1-15, 24-37
DisProt Annotation
TM Helix Prediction No TM helices