Search by BoMiProt ID - Bomi10043


Primary Information

BoMiProt ID Bomi10043
Protein Name Trichohyalin-like protein 1
Organism Bos taurus
Uniprot IdA6QP92
Milk FractionWhey
Ref Sequence Id NP_001193524.1
Aminoacid Length 872
Molecular Weight 95773
Fasta Sequence https://www.uniprot.org/uniprot/A6QP92.fasta
Gene Name TCHHL1
Gene Id 518825
Protein Existence Status reviewed

Secondary Information

Protein Function expressed in the basal layer of the normal epidermis.associated with the proliferation and antiapotosis of keratinocytes.
Biochemical Properties TCHHL1 contains an EF-hand domain in the N-terminus, one trans-membrane domain and a nuclear localization signal. 
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 83-115, 140-217, 252-461, 508-621, 665-839, 860-872
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Yamakoshi T, Makino T, Ur Rehman M, Yoshihisa Y, Sugimori M, Shimizu T. Trichohyalin-like 1 protein, a member of fused S100 proteins, is expressed in normal and pathologic human skin. Biochem Biophys Res Commun. 2013 Mar 1;432(1):66-72. doi: 10.1016/j.bbrc.2013.01.084. Epub 2013 Jan 29. PMID: 23376073.