Search by BoMiProt ID - Bomi10001


Primary Information

BoMiProt ID Bomi10001
Protein Name Transmembrane protein 180/Major facilitator superfamily domain-containing 13A
Organism Bos taurus
Uniprot IdQ58CT4
Milk FractionWhey
Ref Sequence Id NP_001014925.1
Aminoacid Length 517
Molecular Weight 57198
Fasta Sequence https://www.uniprot.org/uniprot/Q58CT4.fasta
Gene Name MFSD13A/TMEM180
Gene Id 514370
Protein Existence Status reviewed

Secondary Information

Protein Function may play an important role in the uptake or metabolism of glutamine and arginine in cancer cell.cation symporter.
Biochemical Properties 12-transmembrane protein. Both the N-terminus and C-terminus of TMEM180 are extracellularly exposed.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 442-458, 501-509
DisProt Annotation
TM Helix Prediction 9 TMHs; (15-37), (101-119), (123-141), (162-184), (196-214), (266-288), (303-325), (332-354), (468-490)
Bibliography Anzai T, Matsumura Y. Topological analysis of TMEM180, a newly identified membrane protein that is highly expressed in colorectal cancer cells. Biochem Biophys Res Commun. 2019 Dec 10;520(3):566-572. doi: 10.1016/j.bbrc.2019.10.070. Epub 2019 Oct 12. PMID: 31615651.