Search by BoMiProt ID - Bomi100


Primary Information

BoMiProt ID Bomi100
Protein Name Cystatin-C
Organism Bos taurus
Uniprot IdP01035
Milk FractionWhey
Ref Sequence Id NP_776454.1
Amino Acid Lenth 148
Molecular Weight 16265
Fasta Sequence https://www.uniprot.org/uniprot/P01035.fasta
Gene Name CST3
Gene Id 281102
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondry Information

Presence in other biological fluids/tissue/cells Parotid glands, osteoblast,
Protein Function Inhibits bone resorption; inhibits such proteases as papain and cathepsin B, L and K;
Significance in milk role in the protection from bacterial infection
PTMs 2 intracellular disulfide bonds; no glycosylation; chicken cystatin is phosphorylated;
Bibliography 1. Matsuoka, Y., Serizawa, A., Yoshioka, T., Yamamura, J., Morita, Y., Kawakami, H., … Kumegawa, M. (2002). Cystatin C in milk basic protein (MBP) and its inhibitory effect on bone resorption in vitro. Bioscience, Biotechnology, and Biochemistry, 66(12), 2531–2536. https://doi.org/10.1271/bbb.66.2531.
2. Mudaliar, M., Tassi, R., Thomas, F. C., McNeilly, T. N., Weidt, S. K., McLaughlin, M., … Zadoks, R. N. (2016). Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), 2748–2761. https://doi.org/10.1039/c6mb00290k.